Prognostic value of von Willebrand factor concentrations in pulmonary hypertension.
نویسندگان
چکیده
1 Klein I, Ojamaa K. Thyroid hormone and the cardiovascular system: from theory to practice. J Clin Endocrinol Metab 1994; 78:1026–1027 2 Gross G, Lues I. Thyroid-dependent alterations of myocardial adrenoreceptors and adrenoreceptor-mediated responses in the rat. Naunyn Schmiedeberg’s Arch Pharmacol 1985; 329: 427–439 3 Drachman DB. Myasthenia gravis and the thyroid gland. N Engl J Med 1962; 266:330–333 4 Millikan CH, Haines SF. Thyroid gland in relation to neuromuscular disease. Arch Intern Med 1953; 92:5–39 5 Teoh R, Chow CC, Kay R, et al. Response to control of hyperthyroidism in patients with myasthenia gravis and thyrotoxicosis. Br J Clin Pract 1990; 44:742–744
منابع مشابه
Frequency Assessment of the H817Q (2451T→A) Variant of von Willebrand Gene in Individuals without Hemorrhagic Signs
Abstract Background and Aims: Von Willebrand disease is a bleeding disorder caused by quantitative or functional defects in von Willebrand factor. The disease is found in up to 1 percent of the population. The most common symptom is mucocutaneous bleeding. Recently, studies conducted on healthy people showed that the H817Q mutation that previously known to cause von Willebrand...
متن کاملPulmonary hypertension secondary to hyperviscosity in a patient with rheumatoid arthritis and acquired von Willebrand disease: a case report
INTRODUCTION Acquired von Willebrand disease is initiated by autoantibodies and hyperviscosity syndrome caused by a massive polyclonal hypergammaglobulinemia. Acquired von Willebrand disease associated with autoimmune disease in addition to pulmonary hypertension during emergency room presentation is a rare condition. To the best of our knowledge, this is the second case reported in the literat...
متن کاملImprovement of von Willebrand factor proteolysis after prostacyclin infusion in severe pulmonary arterial hypertension.
BACKGROUND The presence of dysfunctional von Willebrand factor (vWF) in pulmonary arterial hypertension (PAH) was suggested to be related to increased proteolysis. METHODS AND RESULTS In 10 patients with severe PAH, we studied the proteolysis of plasma vWF (vWF levels, multimeric distribution, proteolytic pattern, and cleaving protease activity) and hemodynamic variables (mean pulmonary arter...
متن کاملBaseline vWF factor predicts the development of elevated pulmonary artery pressure in systemic sclerosis
OBJECTIVES This study aims to examine the utility of von Willebrand factor (vWF) as a biomarker in lcSSc, in particular the ability of vWF to predict the future development of disease manifestations in this disease. METHODS vWFAg concentrations were measured in the serum of patients with lcSSc at baseline and at 3 years, during the QUINs trial [Prevention of Vascular Damage in Scleroderma wit...
متن کاملPlatelet activation risk index as a prognostic thrombosis indicator
Platelet activation in blood flow under high, overcritical shear rates is initiated by Von Willebrand factor. Despite the large amount of experimental data that have been obtained, the value of the critical shear rate, above which von Willebrand factor starts to activate platelets, is still controversial. Here, we recommend a theoretical approach to elucidate how the critical blood shear rate i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chest
دوره 118 4 شماره
صفحات -
تاریخ انتشار 2000